Clobetasol Propionate 0.05% + Lactic Acid 3% + Salicylic acid 6% + Urea 10% OintmentClobival-Plus

How Clobival-Plus works

This is a combination, and each component handles a different part of the problem. Clobetasol propionate is a super-potent topical corticosteroid. It enters the skin cell, binds the glucocorticoid receptor and switches off the genes producing inflammatory mediators, so redness, thickening and itch subside quickly. Potency of this order is reserved for thick, resistant plaques and for short courses, because prolonged use thins the skin. Salicylic acid, Urea and Lactic acid loosen the bonds holding dead surface cells together, so thickened scale lifts away instead of building up. In a combination this also matters for the other ingredient: once the scale is gone, an antifungal or a steroid can actually reach the skin underneath rather than sitting on top of it. Urea does double duty: at higher strengths it softens hard keratin, and at any strength it draws water into the skin and holds it there. Infected, inflamed skin rarely has a single cause, which is why these are formulated together rather than applied one after another.